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Open Access Research article

Attitudes among healthcare professionals to the reporting of adverse drug reactions in Nepal

Santosh KC12, Pramote Tragulpiankit1*, Sarun Gorsanan3 and I Ralph Edwards4

Author Affiliations

1 Faculty of Pharmacy, Mahidol University, Bangkok, Thailand

2 Bir Hospital, Kathmandu, Nepal

3 Faculty of Pharmacy, Siam University, Bangkok, Thailand

4 Uppsala Monitoring Centre, Uppsala, Sweden

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BMC Pharmacology and Toxicology 2013, 14:16  doi:10.1186/2050-6511-14-16

Published: 8 March 2013

Abstract

Background

Healthcare professional’s knowledge and attitudes to adverse drug reaction (ADR) and ADR reporting play vital role to report any cases of ADR. Positive attitudes may favour ADR reporting by healthcare professionals. This study was aimed to investigate the attitudes towards and ways to improve adverse drug reaction (ADR) reporting among healthcare professionals working at four Regional Pharmacovigilance Centres (RPCs) of Nepal.

Methods

A cross sectional study was done by survey using a self-administered structured questionnaire. The questionnaire was distributed to 450 healthcare professionals working at four RPCs.

Results

The overall response rate was 74.0%. There were 74.8% of healthcare professionals who had seen patient experiencing an ADR; however, only 20.1% had reported. Reporting form not available (48.1%) and other colleagues not reporting ADR cases (46.9%) would significantly discourage the ADR reporting among healthcare professionals working at four RPCs. Healthcare professionals perceived that seriousness of the reaction (75.6%); unusual reaction (64.6%); reaction to new product (71.2%); new reaction to existing product (70.2%); and confidence in diagnosis of ADR (60.8%) were important factors on the decision to report ADR. Awareness among healthcare professionals (85.9%), training (76.0%), collaboration (67.0%), and involve pharmacist for ADR reporting (63.1%) were mostly recognized ways to improve reporting. Regular newsletter on current awareness in drug safety (71.2%), information on new ADR (65.8%), and international drug safety information (64.0%) were the identified feedbacks they would like to receive from the Nepal pharmacovigilance programme.

Conclusion

Healthcare professionals working at four RPCs of Nepal have positive attitudes towards ADR reporting. Awareness among healthcare professionals, training and collaboration would likely improve reporting provided they would receive appropriate feedback from the national pharamcovigilance programme.

Keywords:
Adverse drug reaction; Attitudes; Healthcare professional; Nepal