Low-intesity MeC and low-intesity DAPI site distribution for equitoxic drug concentrations. For the two cell lines, the responding distributions of LIM and LID sites are quite similar between equitoxic drug concentrations: LID distributions did not notably vary between the two concentrations as much as LIM distributions did between IC10 and IC50 concentrations. However, a slight difference in LIM distribution was measured for DU145 at IC50: at 500 μM LIM distribution seemed more similar to distribution at IC10.
Gertych et al. BMC Pharmacology and Toxicology 2013 14:11 doi:10.1186/2050-6511-14-11