Electrostatic solvation energy calculation of 1HVC using 4 different force fields. (A)-(D) Calculated electrostatic solvation energies using AMBER, CHARMM, OPLS, and PARSE force fields. (E) All of the 4 results are shown in one figure to show the differences. (F) Electrostatic potential surface of HIV-1 protease [PDB:1HVC], generated by using AMBER force field.
Li et al. BMC Biophysics 2012 5:9 doi:10.1186/2046-1682-5-9