Power of detection without noise. The power of detection vs. the ratio rd/ℓ is plotted for D = 0.05 μm2/s (open circles) and D = 0.1 μm2/s (asterisk). The results for the confined-free motion scheme are shown in the upper panel and those for the free-confined motion scheme are presented in the lower panel. As expected, the power of detection increases considerably as the total number of frames, M, increases. In both panels, the lower solid and dashed lines represent the results for M = 11 and M = 15, respectively. The upper solid and dashed lines are used to express the results for M = 25 and M = 50, respectively.
Menchón et al. BMC Biophysics 2012 5:4 doi:10.1186/2046-1682-5-4