Resolution:
## Figure 7.
Spherical cells can support gradients along the source/sink axis.A) Schematic of a spherical cell of radius r_{s}with oppositely localized kinase and phosphatase spread over a spherical cap. B) 3D mathematical modeling of the distribution of [R ∼ P] in a spherical cell with
radius r_{s} = 0.4 μm. C) [R ∼ P] line scan through the cell middle showing average volume-weighted density
along the cell length (along the dashed line in A) for different radii r_{s}. D) Schematic of 1D distributions of kinase and phosphatase activities that produce
profiles mimicking those in (C) for r_{s}> 0.5 μm, with background kinase and phosphatase activities localized from the middle of
the cell to the phosphatase pole and kinase pole, respectively, and overlapping by
L/20.
Tropini |