Resolution:
## Figure 10.
Spatial gradients are sensitive to cell constriction only when the septum provides
a significant diffusion barrier.A) Schematic of a dividing cell with oppositely localized kinase and phosphatase. f_{a}is the ratio of the area of the pore at the constriction site to the cross-sectional
area in the cylindrical portion of the cell. B) 3D mathematical modeling of the distribution of [R ∼ P] in a dividing cell with
f_{A}=0.3. B) [R ∼ P] line scan through the cell middle showing volume-weighted average density
along cell length for varying constriction sizes. D) Schematic of 1D distribution of kinase and phosphatase activities that produce profiles
mimicking those in (C) for f_{A} < 0.1 μm, with background kinase and phosphatase localized at the middle of the cell and
overlapping by L/10.
Tropini |