Figure 2.

Effect of Fg concentration on integrin cluster size. The upper panels show example empirical frequency distributions for integrin cluster size in cells adhering to (a) 2 μg/mL Fg and (b) 200 μg/mL Fg along with the corresponding lognormal distributions. The lognormal distribution parameters, which were determined via maximum likelihood estimation from integrin cluster sizes in cells adhering to 2-200 μg/mL Fg, are shown in (c) and (d) along with 95% confidence intervals on the parameter estimates. (e) shows the calculated expected (mean) value for the distribution of integrin cluster sizes in cells adhering to each Fg concentration and (f) shows the median value of the integrin cluster sizes in cells adhering to each Fg concentration.