The three-helix-bundle protein GS-α3 W. (a) Variation of histogram of bRMSD with temperature. At high temperatures, there is a broad distribution of bRMSD with values > 10 Å. At lower temperatures there are three clearly separated clusters. Representative structures from these clusters are also shown (color) aligned with the native structure (gray). (b) Temperature dependence of specific heat, Cv, and the ratio hr of the observed helix content and the helix content of the native structure.
Irbäck et al. PMC Biophysics 2009 2:2 doi:10.1186/1757-5036-2-2