Table 1 |
|
Severe reactions to Inactivated Measles and RSV Vaccines |
|
Following exposure, vaccinees had exaggerated disease in lungs. |
|
|
|
Pathology included immune complex deposition and high replication in the lungs. |
|
|
|
Vaccines elicited non-protective, low avidity, waning antibodies. |
|
|
|
Vaccines elicited strong CD4+ proliferation with a Th2 cytokine response, including IL-13 |
|
|
|
Caused cessation of use of both vaccines |
|
|
|
Plotkin Journal of the International AIDS Society 2009 12:2 doi:10.1186/1758-2652-12-2 |