Dose-response curves showing differential radio-sensitivity of human chromosome 1 and human chromosome 2 with respect to aberration induction in lymphocytes as detected by metaphase FISH analysis after exposure to 60Co γ-rays. The dose-effect relationship is best described by Y = α D + β D2, where α and β are the coefficients of the fitted curve. The α coefficients of aberration dose-response curves are 0.0315 ± 0.0235 and 0.0663 ± 0.0361 for chromosome 1 and 2, and β coefficients of aberration dose-response curves are 0.0228 ± 0.0046 and 0.0197 ± 0.0071 for chromosome 1 and 2, respectively.
Pathak et al. BMC Medical Physics 2009 9:6 doi:10.1186/1756-6649-9-6