Magnetic resonance image and pathological examination of a patient with breast cancer that metastasized to the left optic nerve region. A–C: Tumor mass (white circle) is seen conflicted in the optic canal, surrounding the optic nerve. D–G: Histopathological examination of biopsied tissue stained with hematoxylin-eosin (HE) and immunohistochemical staining (original magnification × 200). D: Infiltrating ductal carcinoma arranged in cords, cluster and trabeculae (HE staining). E: Cytokeratin staining as an epithelial cell marker. F: Estrogen receptor staining. G: GCDFP-15 staining as an apocrine cell marker.
Tamai et al. BMC Research Notes 2013 6:546 doi:10.1186/1756-0500-6-546