Table 1

LS associated with autoimmune diseases, presence of autoantibodies, treatment and response
Case Age, sex Morphea’s location Associated autoimmune condition Positive autoantibodies Treatment Response to treatment Ref.
1 48-year-old woman Plaques over the trunk Vitiligo, Hashimoto’s thyroiditis Antithyroglobu- lin antibody, anti-thyroid peroxidaz Not described Not described 3
2 16-year-old girl On her trunk and right arm. Necrotizing vas- culitis of arterioles within the subcutaneous fat and muscles. Mononeuritis multiplex. Lupus anticoaglant test, Anti-DNA antibody, (LE) test, Anticardiolipin-β2GPI antibody Pulse therapy with 1 g methyl prednisolone for 3 days, cyclophosphamide (50 mg/d). Gradually improved 13
3 16-year-old girl Umbilical region, right hemi thorax and back of the right hand Idiopathic thrombocytopenic purpura ANAS, Anti DNA Not described Not described 6
4 22-year-old woman Anterior chest Idiopathic thrombocytopenic purpura None Not described Not described 6
Our case 53 year old woman Atrophic violaceous plaques in the lower limbs Vitiligo, autoimmune hypothyroidism, neumonitis, autoimmune thrombocytopenic purpura and central nervous system vasculitis Anti-microsomal and Anti-thyroglobulin antibodies Methylprednisolone 1 gr/day per five days) and intravenous cyclophosphamide (1 gr monthly Clinical improvement

Bonilla-Abadía et al.

Bonilla-Abadía et al. BMC Research Notes 2012 5:689   doi:10.1186/1756-0500-5-689

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