Common profile 2 for genomic trinucleotide frequencies and the average profile of its corresponding random sequences. Common profile 2 was obtained as the average of similar trinucleotide frequency profiles of 160 prokaryotic genomes (chromosomes) with GC content ranging from 58.02% to 74.91%. Alongside common profile 2 is the average trinucleotide frequency profile of 90 random sequences with GC content of 58%–75% and generated according to first-order symmetry. For other explanations see Figure 1.
Zhang and Wang BMC Research Notes 2012 5:639 doi:10.1186/1756-0500-5-639