Table 5 |
|||
| Assignment of Transcription Factors to robust modules | |||
| Module | TFs in a module in the AC and identified by “Module-to-Regulator” analysis | TFs in a module in the AC landscape only | Top 10 TFs identified by the “Module-to-Regulator” analysis only1 |
| Muscle | none | none | KLF9, COPS5, HIF1AN, PREB, TCF7L2, SMARCA1, SMARCAD1, CHD1, CSDA, MEOX2 [23] |
| Mitochondrial | COPS5 [25] | none | SMARCAD1, CHD1, TCF7L2, HIF1AN2, SMARCA1, BPTF, PREB, MEOX2, YBX1 [26] |
| Ribosomal | none | none | BTF3, GTF2H5, CAMTA1, ZHX1, YY1 [29], BMI1, NR3C1, SUB1, ZBTB1, RBL2 |
| Regulation of ubiquitin–protein ligase activity | BPTF | SUZ12 | TCEB1, TAF9, COPS5 [30], SMAD5, SOX4 [31], JMJD1C, TCF4 [32], SMARCE1, NCOA1 |
| Translation | BTF3 | none | YBX1, TAF10, PHB2, ASH1L, TULP4, TBX3, RBM39, MLL3, RBL2 |
1 In descending order of strength of absolute average correlation coefficient. References providing experimental evidence supporting our computational output are provided.
2TFs also identified in the presumed equivalent module in the bovine AC landscape are in bold.
Sun et al. BMC Research Notes 2012 5:632 doi:10.1186/1756-0500-5-632
