Table 4

Location of the genes encoding muscle structural protein subunits in the AC landscape
Module name Slow twitch fibres1 Fast twitch fibres Both slow and fast twitch fibres Fibre type specificity is not known
Muscle MYL2 TNNT3 TNNT1, FHL1, TMOD4, MYOZ1
Near “muscle” TTN1 MYH2 ACTN2 TRIM54, TCAP, MYOT, DES, MYBPC1
Near “mitochondrial” TNNC2, MYLPF, MYL1 SMPX
Near “regulation of ubiquitin–protein ligase activity” ACTA12
Near “translation” TPM1
Elsewhere in AClandscape OBSCN, NEB, DMD, ANKRD1
Not in the AClandscape MYL3, MYH7, TNNC1, TNNI1, TPM3 MYH1, MYBPC2, TNNI2, MYBPH, ACTN3 MYOM2, MYOM3, MYBPC3, TNNI3, TNNT2, TPM2, MYPN, KBTBD10, KBTBD5, CSRP3, LMOD2, UNC45B, SGCA, CMYA5, PDLIM3, LRRC39, XIRP2, TRIM63

1Fibre type assignments of proteins are from [13], except for TMOD1 and TMOD4 [14] and MYL6B [15].

2Expression of genes encoding proteins in bold are negatively correlated with the majority of the members of the module.

Sun et al.

Sun et al. BMC Research Notes 2012 5:632   doi:10.1186/1756-0500-5-632

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