Table 3

Associated SNPs after correction with asthma-related phenotypes
Gene/ Corr. thresholda SNP Allele MAFb Asthma Atopy Atopic asthma
Famc Z P value Fam Z P value Fam Z P value
AGC1 /0.001 rs11630178 T/C 0.34 99 2.69 0.0070 82 3.59 0.0003 85 3.90 0.0001
IFI6 /0.025 rs11247653 A/G 0.43 133 −2.35 0.0186 109 −1.77 0.0770 110 −1.90 0.0570
ADRA2A /0.025 rs11195299 G/A 0.06 56 −2.59 0.0097 54 −0.79 0.4283 53 −1.92 0.0527
ADH1B /0.003 rs13103321 G/T 0.48 135 −3.04 0.0024 114 −2.57 0.0103 114 −2.62 0.0088

a Corrected threshold for multiple testing (considering independent tagSNPs and phenotypes).

b Minor allele frequency observed in the sample.

c Number of families that contributed to the test.

SNP= Single nucleotide polymorphism; MAF= Minor allele frequency; Fam= Families.

Vaillancourt et al.

Vaillancourt et al. BMC Research Notes 2012 5:630   doi:10.1186/1756-0500-5-630

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