Open Access Short Report

Clinical outcome of skin yaws lesions after treatment with benzathinebenzylpenicillin in a pygmy population in Lobaye, Central African Republic

Alexandre Manirakiza1*, Susana Vilas Boas2, Narcisse Beyam3, Germain Zadanga1, François Xavier Konamna1, Siméon P Njuimo1 and Rémi Laganier1

Author Affiliations

1 Institut Pasteur de Bangui, PO Box 923, Bangui, Central African Republic

2 Poste de santé de Mongoumba, Bangui, Central African Republic

3 United Nations Population Fund, Bangui, Central African Republic

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BMC Research Notes 2011, 4:543  doi:10.1186/1756-0500-4-543

Published: 15 December 2011



Yaws is a bacterial skin and bone infectious disease caused by Treponema pallidum pertenue. It is endemic, particularly among pygmies in Central African Republic. To assess the clinical cure rate after treatment with benzathinepenicillin in this population, we conducted a cohort survey of 243 patients in the Lobaye region.

Findings and conclusion

The rate of healing of lesions after 5 months was 95.9%. This relatively satisfactory level of therapeutic response implies that yaws could be controlled in the Central African Republic. Thus, reinforcement of the management of new cases and of contacts is suggested.

Yaws; Treatment; Central African Republic