BMC Research Notes


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The proximal first exon architecture of the murine ghrelin gene is highly similar to its human orthologue

Inge Seim, Shea L Carter, Adrian C Herington and Lisa K Chopin*

Author Affiliations

Institute of Health and Biomedical Innovation, Queensland University of Technology, Kelvin Grove, Queensland, Australia

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BMC Research Notes 2009, 2:85 doi:10.1186/1756-0500-2-85

Published: 9 May 2009

Additional files

Additional file 1:

Compilation of exons and exon-intron boundaries of the murine ghrelin gene. This is a PDF listing exons and intron boundaries of mouse ghrelin locus derived transcripts. Exon and intron sizes (bp) are indicated. Experimental evidence and/or references to the literature for each exon are shown. Note that exons 1b-e correspond to 5' extended exon 1 sequences.

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Open Data

Additional file 2:

Compilation of 5' UTR sequences of the murine ghrelin gene. Compilation of 5' UTR sequences of the murine ghrelin gene (Ghrl) based on 5' RACE clones obtained in this study. The length (AA) of putative upstream open reading frames (uORF) corresponds to the distance from the start codon of preproghrelin to the transcription start site. The minimum free energies (ΔG) of the 5' UTRs were calculated using the RNAfold web server [18]. The more negative the minimum free energy an RNA structure has, the more secondary structure the RNA is likely to have.

Format: PDF Size: 17KB Download file

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Open Data