Blind search for post-translational modifications and amino acid substitutions using peptide mass fingerprints from two proteases
-
* Corresponding author: Harald Barsnes harald.barsnes@ii.uib.no
1 Department of Informatics, University of Bergen, PB 7803, N-5020 Bergen, Norway
2 Institute for Cancer Research, The Radium Hospital, The National Hospital Medical Center, Montebello, N-0310 Oslo, Norway
BMC Research Notes 2008, 1:130 doi:10.1186/1756-0500-1-130
Published: 19 December 2008Additional files
Additional file 1:
Theoretical Examples. A PDF file containing examples showing detection of modifications in an artificial dataset.
Format: PDF Size: 45KB Download file
This file can be viewed with: Adobe Acrobat Reader
Additional file 2:
Experimental Examples. A PDF file containing details on MS experiments performed to show the proposed usage of the algorithm and software tool.
Format: PDF Size: 108KB Download file
This file can be viewed with: Adobe Acrobat Reader
Additional file 3:
Supplementary Material. A PDF file containing additional information regarding a theoretical analysis of the degree of coverage and overlap between the proteases trypsin, chymotrypsin and gluC using 19,852 human proteins.
Format: PDF Size: 7.4MB Download file
This file can be viewed with: Adobe Acrobat Reader
