Table 1

Prostate cancer datasets analyzed



Samples Analyzed




Normal vs Tumor

Authors examined 61 microdissected prostate cancer specimens along with 63 normal prostate tissues samples adjacent to tumor of patients.

Feature Selection



Normal vs Tumor

Authors examined 33 African-American and 36 European-American patients with prostate cancer. Also profiled 18 non-tumor prostate tissues from 7 African-American and 11 European-American patients.

Feature Selection



Normal vs Tumor

Comprehensive set from Memorial Sloan Ketting tumor bank in prostate tumors from 53 patients with primary or metastatic prostate cancer and 29 normal controls.

Feature Selection



Disease free interval survival

79 tumors were obtained from the Memorial Sloan Kettering tumor bank. The authors identified three signatures of early recurrence (within one year).

Validation Set

From author

The first three datasets are used for mechanism feature selection reported in Table 2 and Figure 1. The fourth dataset serves as independent validation as depicted in Figure 3.

Chen et al. BMC Medical Genomics 2013 6(Suppl 2):S4   doi:10.1186/1755-8794-6-S2-S4

Open Data