Network diagram of CPE-related genes (top panel) and NCI-related genes (bottom panel) in white matter. Input genes from Table 2 are indicated by solid black circles. The diamond-shapes are neighboring genes that are identified by literature-based associations. There are various types of interactions among the genes represented as lines and dotted lines in color as follows: Down-regulation – red; Up-regulation – green; Regulation – grey; Co-expression – purple; Physical Interaction – brown; Predicted Protein Interaction – dotted aquamarine; Predicted Transcription Factor Regulation – dotted brown.
Levine et al. BMC Medical Genomics 2013 6:4 doi:10.1186/1755-8794-6-4