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Open Access Highly Accessed Research article

Identification of potential synthetic lethal genes to p53 using a computational biology approach

Xiaosheng Wang1 and Richard Simon2

Author Affiliations

1 Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, NE, USA

2 National Cancer Institute, National Institutes of Health, Biometric Research Branch, Rockville, MD, USA

BMC Medical Genomics 2013, 6:30  doi:10.1186/1755-8794-6-30

Published: 11 September 2013

Additional files

Additional file 1: Table S1:

The p53 mutation information for the NCI-60 cancer cell lines, the TCGA tumor samples and the CCLE cancer cell lines.

Format: XLS Size: 130KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 2: Table S2:

The identified candidate synthetic lethal genes to p53.

Format: XLS Size: 54KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data