Table 6

Ten most up-regulated pathways by insulin in the insulin-resistant group

GO category

Pathway name

Nominal p

Permuted p


GO:0016125

sterol metabolic process

1.52E-08

0.0001


GO:0006629

lipid metabolic process

2.31E-08

0.0001


GO:0008203

cholesterol metabolic process

1.12E-07

0.0001


GO:0044255

cellular lipid metabolic process

1.36E-07

0.0001


GO:0008202

steroid metabolic process

6.34E-07

0.0001


GO:0016126

sterol biosynthetic process

4.45E-06

0.0002


GO:0006694

steroid biosynthetic process

4.93E-06

0.0001


GO:0001889

liver development

6.62E-06

0.0002


GO:0008015

blood circulation

1.00E-05

0.0002


GO:0042127

regulation of cell proliferation

1.77E-05

0.0006


Soronen et al. BMC Medical Genomics 2012 5:9   doi:10.1186/1755-8794-5-9

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