Table 3

Ten most up-regulated pathways in insulin-resistant compared to insulin-sensitive group during euglycemic hyperinsulinemic conditions

GO category

Pathway name

Nominal p

Permuted p


GO:0001934

positive regulation of protein amino acid phosphorylation

6.70E-08

0.0001


GO:0000904

cell morphogenesis during differentiation

1.62E-07

0.0001


GO:0048675

axon extension

2.63E-07

0.0001


GO:0006954

inflammatory response

3.71E-07

0.0001


GO:0005764

lysosome

6.78E-07

0.0001


GO:0010562

positive regulation of phosphorus metabolic process

7.14E-07

0.0001


GO:0005773

vacuole

7.18E-07

0.0001


GO:0002682

regulation of immune system process

1.02E-06

0.0001


GO:0006955

immune response

1.6E-07

0.0001


GO:0001932

regulation of protein amino acid phosphorylation

1.8E-07

0.0001


Soronen et al. BMC Medical Genomics 2012 5:9   doi:10.1186/1755-8794-5-9

Open Data