The association between hypermethylation and LOH/LOI. (A) IGF2/H19 DMR. The rate of DNA methylation (mean ± SD) of cases with LOH/LOI of either IGF2 or H19 and MOI were compared. For this analysis, one case which H19 was MOI and IGF2 was LOI, was removed. (B) PEG1 DMR. Statistically significant differences between groups are analyzed with ANOVA followed with multiple comparison method (Tukey's HSD test), presented as the P-value (*P < 0.01). Norm: Normal ovarian tissues.
Hiura et al. BMC Medical Genomics 2012 5:8 doi:10.1186/1755-8794-5-8