Figure 2.

2D-DIGE analysis of metastatic 5-8F versus nonmetastatic 6-10B cells. A. A representative two-color merged 2D-DIGE gel image. Green is the Cy3-labeled metastatic 5-8F cell sample. Red is the Cy5-labeled 6-10B cell sample. B. Labeled differentially expressed proteins (DEPs) between metastatic (5-8F) and nonmetastatic (6-10B) cell mitochondria (Ratio = 5-8F/6-10B; Red: down-regulated; Green: up-regulated). C. Three-dimensional simulation, a close-up of the region of 2D-DIGE gel image, and the associated graph view of a representative up-regulated protein in metastatic 5-8F cell mitochondria (spot 2). D. Three-dimensional simulation, a close-up of the region of 2D-DIGE gel image, and the associated graph view of a representative down-regulated protein in metastatic 5-8F cell mitochondria (Spot 15).

Liu et al. BMC Medical Genomics 2012 5:62   doi:10.1186/1755-8794-5-62
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