Table 3

Genes with high module membership in the Finnish twins, Mexican, and METSIM triglyceride modules
3 Triglyceride module overlap Gene(s) Empirical p-value
1 gene with module membership* > 0.9 CCR1 6.18 × 10-4
2 genes in top 50 module membership HCST, FERMT3 2.46 × 10-6
3 genes in top 25% module membership CCR1, CXCL16, HCST < 10-7
7 genes in top 50% module membership CCR1, CXCL16, HCST, ARHGAP30, FERMT3, RNASET2, SELPG < 10-7

*Module membership indicates the correlation coefficient between the module eigengene and gene expression.

The triglyceride modules referenced above are the brown METSIM module, the blue Finnish Twin module, and the yellow Mexican module. P-values were calculated empirically by randomly selecting the observed number of genes satisfying the module membership criteria and observing the number of overlaps occurring by chance.

Haas et al.

Haas et al. BMC Medical Genomics 2012 5:61   doi:10.1186/1755-8794-5-61

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