Table 2 |
|||
| The most differentially expressed genes using conventional gene expression analysis overlap between the three studies | |||
| p-values | |||
| Group | Top 100 Genes* | Top 250 Genes | Top 500 Genes |
| Finnish Twins, Mexicans | 2.81 × 10-33 | 2.01 × 10-69 | 6.51 × 10-103 |
| METSIM, Finnish Twins | 3.27 × 10-6 | 5.96 × 10-7 | 5.22 × 10-10 |
| METSIM, Mexicans | 2.11 × 10-4 | 2.48 × 10-5 | 2.24 × 10-8 |
*Genes were sorted in descending order by the difference in the average normalized gene expression values between the high and low TG groups. The overlap p-values were calculated using a two-tail Fisher’s exact test. All p-values pass the Bonferroni correction for the nine statistical tests performed (p-value<5.6 x 10-3).
Haas et al. BMC Medical Genomics 2012 5:61 doi:10.1186/1755-8794-5-61
