## Table 8 |
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Ten most significant KEGG pathways from the gene set enrichment analysis of the genome |
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KEGG Identifier |
KEGG Pathway |
Over-Expressed Gene^{1} |
Under-Expressed Genes^{2} |
Log Odds Ratio^{3} |
FDR P-value^{4} |

hsa03010 | ribosome | 119 | 16 | −2.4779 | 9.7E-10 |

hsa00010 | glycolysis / gluconeogenesis | 57 | 27 | −1.1614 | 3.6E-04 |

hsa00190 | oxidative phosphorylation | 103 | 39 | −0.9392 | 3.6E-04 |

hsa05212 | pancreatic cancer | 54 | 45 | −0.9460 | 4.7E-04 |

hsa05130 | pathogenic escherichia coli infection | 44 | 41 | −1.0575 | 4.7E-04 |

hsa00240 | pyrimidine metabolism | 42 | 78 | −0.8800 | 5.0E-04 |

hsa03050 | proteasome | 33 | 32 | −1.0965 | 7.2E-04 |

hsa00280 | valine, leucine and isoleucine degradation | 20 | 48 | −1.1353 | 8.5E-04 |

hsa04662 | b cell receptor signaling pathway | 34 | 65 | −0.9084 | 8.5E-04 |

hsa05223 | non-small cell lung cancer | 25 | 52 | −0.9922 | 9.0E-04 |

^{1}Over-Expressed Genes: number of genes that have a positive association between expression
and glioblastoma multiforme survival.

^{2}Under-Expressed Genes: number of genes that have a negative association between expression
and glioblastoma multiforme survival.

^{3}Log Odds Ratio: indicates whether the category is more enriched among the genes that
have a positive association between expression and survival relative to the enrichment
among the genes that have a negative association between expression and glioblastoma
survival (positive log_{e} odds ratio) or vice versa (negative log_{e} odds ratio). Extreme values indicate higher difference in the enrichment percentages
between the positive and negative association groups meanwhile values close to zero
indicate similar enrichment percentages between positive and negative association
groups.

^{4}FDR-adjusted P-value: False discovery rate adjusted P-value of the log odds ratio
test.

Sadeque * et al.*

Sadeque * et al.* *BMC Medical Genomics* 2012 **5**:59 doi:10.1186/1755-8794-5-59