Table 2

Genes that correlated with IA, HI scale or both in the current study previously associated with ADHD in published genetic studies
Gene symbol Gene title P-value (HI) rp(HI) P-value (IA) rp (IA) Reference
Common IAHI genes
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.015 −0.54 0.043 −0.47 [14]
SLC6A2 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 0.006 0.58 0.023 0.50 [15]
HI-associated genes
BCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.015 −0.44 [16]
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 0.048 0.45 [6]
AR androgen receptor 0.041 0.46 [5]
ARRB2 arrestin, beta 2 0.006 0.62
COMT Catechol-O-methyltransferase 0.015 −0.58 [17]
DRD2 dopamine receptor D2 0.007 0.44 [17]
HES1 hairy and enhancer of split 1, (Drosophila) 0.002 −0.60 [17]
LPL lipoprotein lipase 0.029 −0.52 [6]
MAOA monoamine oxidase A 0.006 −0.57 [17]
NOS1 nitric oxide synthase 1 (neuronal) 0.004 −0.62 [18]
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.009 0.53 [19]
PPM1F protein phosphatase 1F (PP2C domain containing) 0.004 0.59 [6]
SLC6A4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 0.006 0.65 [17]
SULF2 sulfatase 2 0.013 0.46 [6]
TFEB transcription factor EB 0.034 0.48 [6]
CCDC136 coiled-coil domain containing 136 0.036 0.409 [20]
ATP11A ATPase, class VI, type 11A 0.018 0.511 [20]
DUSP1 dual specificity phosphatase 1 0.014 0.551 [21]
SH3BGRL2 SH3 domain binding glutamic acid-rich protein like 2 0.001 0.697 [22]
IA-associated genes
FOXP1 forkhead box P1 0.001 −0.62 [6]
FADS2 fatty acid desaturase 2 0.011 −0.52 [23]
DRD1 dopamine receptor D1 0.049 0.44 [24]
MOBP myelin-associated oligodendrocyte basic protein 0.010 0.48 [6]
PPM1H protein phosphatase 1H (PP2C domain containing) 0.035 0.47 [20]
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 0.007 −0.51 [20]

Tian et al.

Tian et al. BMC Medical Genomics 2012 5:49   doi:10.1186/1755-8794-5-49

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