Open Access Research article

Integrative analysis of neuroblastoma and pheochromocytoma genomics data

Peter M Szabó1, Miklós Pintér2, Diana Rita Szabó1, Adrienn Zsippai1, Attila Patócs3, András Falus4, Károly Rácz1 and Peter Igaz1*

Author Affiliations

1 2nd Department of Medicine, Faculty of Medicine, Semmelweis University, Szentkirályi str. 46, Budapest, H-1088, Hungary

2 Department of Mathematics, Corvinus University of Budapest, Fővám sqr. 8, Budapest, H-1093, Hungary

3 Molecular Medicine Research Group, Hungarian Academy of Sciences, Szentkirályi str. 46, Budapest, H-1088, Hungary

4 Department of Genetics, Cell- and Immunobiology, Semmelweis University, Nagyvárad sqr. 4, Budapest, H-1089, Hungary

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BMC Medical Genomics 2012, 5:48  doi:10.1186/1755-8794-5-48

Published: 29 October 2012

Additional files

Additional file 1:

Significantly enriched pathways of the Ingenuity Pathway Analysis in different comparisons. Ratio is calculated as follows: number of significanty differentially expressed genes in a given pathway, divided by total number of genes that make up that pathway.

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Additional file 2:

Significant gene expression changes between NB or PCC and other normal tissues and tumors (positive fold change values are marking the up-, negatives the downregulated genes in NB or PCC). Genes are ranked by the number of significant expression changes between NB or PCC and other normal tissues and tumors.

Format: XLS Size: 3MB Download file

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Additional file 3:

Similar gene expressions among NB and PCC. Genes are ranked by their incidence in the different studies.

Format: XLS Size: 23KB Download file

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Additional file 4:

Common gene expression changes between NB and PCC (positive fold change values mark the up-, negatives the downregulated genes in PCC). Genes are ranked by the incidence of significant expression changes among the different studies.

Format: XLS Size: 127KB Download file

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Additional file 5:

Common gene expression changes between different subgroups of NB (positive fold change values mark the up-, negatives the downregulated genes in late stage, MYCN-amplified or unfavorable NB). Genes are ranked by the incidence of significant expression changes among the different studies.

Format: XLS Size: 168KB Download file

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Additional file 6:

Common gene expression changes between SDH/VHL- and RET/NF1-related PCC (positive fold change values mark the up-, negatives the downregulated genes in RET/NF1-related PCC). Genes are ranked by the incidence of significant expression changes among the different studies.

Format: XLS Size: 55KB Download file

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Additional file 7:

Common gene expression changes between MEN2A- and VHL-related PCC (positive fold change values mark the up-, negatives the downregulated genes in VHL-related PCC). Genes are ranked by the incidence of significant expression changes among the different studies.

Format: XLS Size: 49KB Download file

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Open Data