Table 1

Patient characteristics
Variable Training set data n = 154 Total (%) Variable Test set data n = 814 Total (%)
Age (years) Median 55.5 Age (years) Median 50.4
(range) 26 – >92 (range) 23.1 – 76.2
Menopausal status Pre 49 (31.8) Menopausal status Pre 439 (53.9)
Post 101 (65.6) Post 375 (46.1)
Unknown 4 (2.6)
Primary tumor size T1 63 (40.9) Primary tumor size T1 338 (41.5)
T2 69 (44.8) T2 430 (52.8)
T3 17 (11.0) T3 46 (5.7)
Unknown 1 (0.6)
Reduction Mamoplasty 4 (2.6)
Nodal status 0 95 (61.7) Nodal status 0 0
1 – 3 54 (35.1) 1 – 3 503 (61.8)
> 3 0 (0) > 3 311 (38.2)
Unknown 1 (0.6)
Reduction Mamoplasty 4 (2.6)
Histopathologic grade* G1 23 (14.9) Histopathologic grade* G1 107 (13.1)
G2 45 (29.2) G2 335 (41.2)
G3 80 (51.9) G3 313 (38.5)
GX 2 (1.3) GX 59 (7.2)
Reduction Mamoplasty 4 (2.6)
Estrogen receptor^ Positive 100 (64.9) Estrogen receptor^ Positive 644 (79.1)
Negative 49 (31.8) Negative 170 (20.9)
Unknown 1 (0.6)
Reduction Mamoplasty 4 (2.6)
Progesterone receptor^^ Positive 82 (53.2) Progesterone receptor^^ Positive 567 (69.7)
Negative 67 (43.5) Negative 247 (30.3)
Unknown 1 (0.6)
Reduction Mamoplasty 4 (2.6)
HER2 status Positive 37 (24.0) HER2 status Positive 116 (14.3)
Negative 111 (72.1) Negative 698 (85.7)
Unknown 2 (1.3)
Reduction Mamoplasty 4 (2.6)
Ki67 IHC Unknown 154 (100) Ki67 IHC Positive 236 (29.6)
Negative 561 (70.4)
PAM50 Intrinsic Subtype Luminal A 53 (34.4) PAM50 Intrinsic Subtype Luminal A 277 (34.0)
Luminal B 27 (17.5) Luminal B 261 (32.1)
HER2-enriched 32 (20.8) HER2-enriched 174 (21.4)
Basal-like 38 (24.7) Basal-like 70 (8.6)
Normal-like 4 (2.6) Normal-like 32 (3.9)

*Grade based on Nottingham-Bloom-Richardson scoring.

^ER positive required at least 10% staining nuclei.

^^PR positive required at least 10% staining nuclei.

#HER2 positive were 3+ IHC or 2+ and CISH confirmed.

Bastien et al.

Bastien et al. BMC Medical Genomics 2012 5:44   doi:10.1186/1755-8794-5-44

Open Data