Receiver Operator Characteristic (ROC) curves for ESR1, PGR, and ERBB2 for the GEICAM/9906 test set. ROC curves for the GEICAM/9906 test set were generated using the clinical IHC status (positive vs. negative) for ER, PR, and HER2/neu as compared to the continuous RT-qPCR data for ESR1, PGR, and ERBB2. The cut-points for sensitivity/specificity are based on the training set.
Bastien et al. BMC Medical Genomics 2012 5:44 doi:10.1186/1755-8794-5-44