Table 1

Characteristic of patients and datasets
Name Dataset origin de Tayrac GSE4271 GSE4412 Lee GSE13041 Verhaak TCGA Data Portal Petalidis GSE2727 Local_1 CHU Rennes CHU Angers Local_2 CHU Rennes
Technology Number of samples Affymetrix Affymetrix Affymetrix Affymetrix Agilent Q-PCR
115 161 173 39 41 57
Gender Male M:65 M:96 M:112 M:29 M:21 M:31
Female F:50 F:65 F:61 F:10 F:20 F:26
Age (y) median [min-max] 48 [18-82] 55 [22-86] 59 [14-87] 61 [22-74] 58 [33-80] 59 [36-78]
<50 65 59 56 14 10 10
> = 50 50 102 117 25 31 47
KPS (%) median - - 90 [40-100] - 80 [40-100] 80 [40-100]
<=70 - - 22 - 15 28
>70 - - 58 - 23 29
NA - - - 3 -
Treatment (surgical) biopsy - - 6 1 2
partial resection - - - 8 17
total resection - 161(a) 164 (c) 26 38
NA - - 1 6 -
Treatment (adjuvant) RT - 3 -
RT + CT like Stupp’s schedule - (b) (b) (c) 37 57
no treatment - 1 -
MGMT status Methylated - 86 42 - 24 27
Un-methylated - 75 122 - 17 29
NA - - - - - 1
IDH1 status Wild-type - - 167 - 39 39
Mutated - - 6 - 2 1
NA - - - - - 17
Subtype Proneural - 41 48 - 12 -
non-Proneural - 120 125 - 29 -

(a) ‘resection mentioned alone with no other details.

(b) Excessively heterogeneous treatment. GBM de novo tumors with no prior treatment.

(c) Data not available.

Vauléon et al.

Vauléon et al. BMC Medical Genomics 2012 5:41   doi:10.1186/1755-8794-5-41

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