Polymorphism in glutamate cysteine ligase catalytic subunit (GCLC) is associated with sulfamethoxazole-induced hypersensitivity in HIV/AIDS patients
1 Department of Pharmacology, Program in Pharmacogenomics, School of Biomedical Science, College of Medicine, Ohio State University, Columbus, OH, 43210, USA
2 Division of Infectious Diseases, Internal Medicine, College of Medicine, Ohio State University, Columbus, OH, 43210, USA
BMC Medical Genomics 2012, 5:32 doi:10.1186/1755-8794-5-32Published: 23 July 2012
Additional file 1 :
Table S1 and S2. Association between promoter SNP rs17883901 or 5’UTR GAG trinucleotide polymorphism in GCLC and SMX-induced hypersensitivity. Distribution of 5’UTR GAG trinucleotide repeats in patients with or without hypersensitivity. Chi-square test P=0.319.
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