Overview of the analysis workflow. This figure shows an overview of the analysis workflow followed in this study as described in the text. From the initial microarray data (orange), three different approaches were pursued (light green). (I) Statistical analysis (II) Co-transcriptional network analysis and (III) Interactome network analysis. Each of these paths ends with a functional analysis (blue), which was combined into a common pathways analysis at the end of the pipeline (purple). Promoter analysis (lavender) was performed afterwards as a validation step for the conclusions from the common pathways analysis. LM = linear models. RAW = unadjusted P-values (not corrected for multiple hypothesis testing).
Diez et al. BMC Medical Genomics 2012 5:27 doi:10.1186/1755-8794-5-27