Table 3

Association between LINE-1 methylation levels and risk of TOF
LINE-1 methylation level TOF (%) Control (%) OR (95% CI) P
(n = 32) (n = 15)
Highest quartile (>75%) 2 (6.3) 4 (26.7) 1.0 (reference)
Medium quartile (25%–75%) 8 (25.0) 8 (53.3) 2.0 (0.3–14.2) 0.65
Lowest quartile (<25%) 22 (68.7) 3 (20.0) 14.7 (1.8–117.7) 0.014

OR, odds ratio; P, percentile; Cutoffs defined as 25% P and 75% P of the control group methylation level.

Sheng et al.

Sheng et al. BMC Medical Genomics 2012 5:20   doi:10.1186/1755-8794-5-20

Open Data