Table 2

Selected atherosclerosis related genes for model derivation.

Probes

Gene_Symbol

Pvalue

Qvalue

Fold change

Predictor for test set

Function


211921_x_at

PTMA

8.88E-08

5.79E-04

1.47

MO/MA

Inflammatory Disease

206788_s_at

CBFB

2.87E-07

7.32E-04

-1.50

MO/MA

Inflammatory Response

207760_s_at

NCOR2

2.49E-07

7.32E-04

1.25

MA

Other Metabolic Processes

218828_at

PLSCR3

2.05E-07

7.32E-04

1.27

MO/WBC

Other Metabolic Processes

201331_s_at

STAT6

2.74E-06

2.18E-03

1.32

MO

Inflammatory Response

201591_s_at

NISCH

2.55E-06

2.18E-03

1.28

MO/WBC

Other Metabolic Processes

205125_at

PLCD1

2.19E-06

2.18E-03

1.22

MO

Other Metabolic Processes

202102_s_at

BRD4

3.25E-06

2.39E-03

1.41

MO/WBC

Other Metabolic Processes

205059_s_at

IDUA

3.94E-06

2.44E-03

1.38

MO/MA

Other Metabolic Processes

212705_x_at

PNPLA2

4.25E-06

2.56E-03

1.36

MO/MA

Lipid Metabolism

203839_s_at

TNK2

4.95E-06

2.88E-03

1.37

MO/MA

Other Metabolic Processes

210969_at

PKN2

5.25E-06

2.95E-03

-1.55

MO

Other Metabolic Processes

207292_s_at

MAPK7

5.67E-06

2.97E-03

1.23

MO

Other Metabolic Processes

211716_x_at

ARHGDIA

5.74E-06

2.97E-03

1.43

MO

Inflammatory Disease

206580_s_at

EFEMP2

6.76E-06

3.24E-03

1.35

MO

Inflammatory Disease

202389_s_at

HTT

7.10E-06

3.25E-03

1.17

WBC

Lipid Metabolism

218961_s_at

PNKP

7.00E-06

3.25E-03

1.22

MO

Other Metabolic Processes

1555214_a_at

CLEC7A

7.61E-06

3.44E-03

-1.89

MO

Inflammatory Response

220088_at

C5AR1

8.96E-06

3.56E-03

1.32

MO

Inflammatory Response

204506_at

PPP3R1 /WDR92

1.01E-05

3.87E-03

-1.51

MO/MA

Other Metabolic Processes

202848_s_at

GRK6

1.25E-05

4.08E-03

1.13

MO

Inflammatory Response

204524_at

PDPK1

1.42E-05

4.25E-03

1.36

MO

Other Metabolic Processes

211537_x_at

MAP3K7

1.55E-05

4.25E-03

-1.28

MO/MA

Inflammatory Response

224883_at

PLDN

1.57E-05

4.25E-03

-1.27

MO

Inflammatory Response

205926_at

IL27RA

1.70E-05

4.30E-03

1.75

MO/MA

Inflammatory Response

202264_s_at

TOMM40

1.90E-05

4.51E-03

1.24

MO/MA

Inflammatory Response

210995_s_at

TRIM23

1.91E-05

4.51E-03

-1.67

MO/MA

Other Metabolic Processes

210809_s_at

POSTN

1.98E-05

4.60E-03

1.19

MO

Inflammatory Disease

207904_s_at

LNPEP

2.08E-05

4.73E-03

-1.60

MO/MA

Other Metabolic Processes

226111_s_at

ZNF385A

2.29E-05

4.95E-03

1.40

MO

Hematological System Development and Function

205400_at

WAS

2.68E-05

5.31E-03

1.48

MO/MA

Lipid Metabolism

203709_at

PHKG2

2.87E-05

5.57E-03

1.21

MA

Other Metabolic Processes

209812_x_at

CASP2

3.02E-05

5.72E-03

-1.26

MO

Lipid Metabolism

221957_at

PDK3

3.48E-05

6.13E-03

-1.34

MO/MA

Other Metabolic Processes

1557145_at

STK38

3.61E-05

6.15E-03

-1.50

Other Metabolic Processes

217888_s_at

ARFGAP1

3.69E-05

6.18E-03

1.19

MO

Inflammatory Disease

204158_s_at

TCIRG1

3.98E-05

6.35E-03

1.28

Immunological Disease

204150_at

STAB1

4.16E-05

6.47E-03

1.46

Inflammatory Response

36936_at

TSTA3

4.17E-05

6.47E-03

1.16

MO/MA

Carbohydrate Metabolism

211652_s_at

LBP

4.51E-05

6.57E-03

1.20

MO

Lipid Metabolism

225647_s_at

CTSC

4.74E-05

6.80E-03

-1.36

MO

Inflammatory Disease

200604_s_at

PRKAR1A

6.14E-05

7.77E-03

-1.54

MO/MA

Other Metabolic Processes

202804_at

ABCC1

6.52E-05

7.80E-03

1.15

MO

Lipid Metabolism

221563_at

DUSP10

6.60E-05

7.82E-03

-1.26

MO

Other Metabolic Processes

207240_s_at

LHCGR

7.14E-05

8.15E-03

1.09

Carbohydrate Metabolism

206217_at

EDA

7.32E-05

8.21E-03

1.32

MO/MA

Other Metabolic Processes

208867_s_at

CSNK1A1

7.69E-05

8.34E-03

-1.39

MA

Other Metabolic Processes

221770_at

RPE

8.05E-05

8.40E-03

-1.29

MO/WBC/MA

Carbohydrate Metabolism

207319_s_at

CDC2L5

8.46E-05

8.70E-03

-1.59

MO/MA

Hematological System Development and Function

207764_s_at

HIPK3

9.28E-05

9.18E-03

-1.57

MO/MA

Other Metabolic Processes

209532_at

PLAA

9.57E-05

9.33E-03

-1.19

MO

Lipid Metabolism

210333_at

NR5A1

9.76E-05

9.43E-03

1.37

MO/WBC/MA

Hematological System Development and Function

205546_s_at

TYK2

1.02E-04

9.67E-03

1.16

MO

Inflammatory Response

207201_s_at

SLC22A1

1.10E-04

9.97E-03

1.33

MO/MA

Other Metabolic Processes

213733_at

MYO1F

1.11E-04

1.00E-02

1.15

Inflammatory Response

214971_s_at

ST6GAL1

1.11E-04

1.00E-02

-1.46

MO/MA

Inflammatory Response


These genes were identified by t-test, biological function analysis and COXEN algorithm

MO: Monocyte (Test set1); WBC: White blood cell (Test set2); MA: Macrophage (Test set3)

Cheng et al. BMC Medical Genomics 2012 5:2   doi:10.1186/1755-8794-5-2

Open Data