Table 9 |
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|
Top ten genes whose transcript levels are correlated with methylation of CpG sites in MSX1, CDK2 and GRB10 |
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|
Tissue |
Methylation Gene |
CpG ID |
Expression Gene |
Transcript ID |
Correlation1 |
Gene Name |
|
|
||||||
|
Blood |
MSX1 |
cg14167596 |
APOE |
ILMN_1740938 |
0.76 |
Apolipoprotein E |
|
cg14167596 |
CGA |
ILMN_1734176 |
0.70 |
Glycoprotein Hormones, Alpha Polypeptide |
||
|
cg03199651 |
KRT6C |
ILMN_1754576 |
0.69 |
Keratin 6 C |
||
|
cg14167596 |
PAPPA |
ILMN_1721770 |
0.67 |
Protein Kinase C And Casein Kinase Substrate in Neurons 1 |
||
|
cg14167596 |
PSG4 |
ILMN_1693397 |
0.67 |
Pregnancy Specific Beta-1-Glycoprotein 4 |
||
|
cg26615830 |
DCN |
ILMN_2347145 |
0.65 |
Decorin |
||
|
cg14167596 |
PSG6 |
ILMN_2309615 |
0.65 |
Pregnancy Specific Beta-1-Glycoprotein 6 |
||
|
cg14167596 |
CSH1 |
ILMN_1693617 |
0.65 |
Chorionic somatomammotropin hormone 1 (placental lactogen) |
||
|
cg14167596 |
GH2 |
ILMN_1659354 |
0.65 |
Growth Hormone 2 |
||
|
cg14167596 |
ADAM12 |
ILMN_1726266 |
0.65 |
ADAM Metallopeptidase Domain 12 |
||
|
Placenta |
CDK2 |
cg04108502 |
CXCL11 |
ILMN_2067890 |
0.74 |
Chemokine (C-X-C Motif) Ligand 11 |
|
cg04108502 |
HLA-DPB1 |
ILMN_1749070 |
0.70 |
Major Histocompatibility Complex, Classii, DP Beta 1 |
||
|
cg04108502 |
CXCL9 |
ILMN_1745356 |
0.68 |
Chemokine (C-X-C Motif) Ligand 9 |
||
|
cg04108502 |
GBP4 |
ILMN_1771385 |
0.68 |
Guanylate Binding Protein 4 |
||
|
cg04108502 |
GBP5 |
ILMN_2114568 |
0.67 |
Guanylate Binding Protein 5 |
||
|
cg04108502 |
UBD |
ILMN_1678841 |
0.66 |
Ubiquitin D |
||
|
cg04108502 |
VCY |
ILMN_1683872 |
0.66 |
Variable charge, Y-linked |
||
|
cg04108502 |
HLA-DRB3 |
ILMN_1717261 |
0.66 |
Major Histocompatibility Complex, Class II, DR Beta 3 |
||
|
cg04108502 |
CD3D |
ILMN_2261416 |
0.65 |
CD3d molecule, delta (CD3-TCR complex) |
||
|
cg04108502 |
CETP |
ILMN_1681882 |
0.65 |
Cholesteryl ester transfer protein, plasma |
||
|
GRB10 |
cg20651681 |
SHROOM2 |
ILMN_1681777 |
0.68 |
Shroom Family Member 2 |
|
|
cg20651681 |
MESDC1 |
ILMN_1781565 |
0.67 |
Mesoderm Development Candidate 1 |
||
|
cg20651681 |
CCDC146 |
ILMN_1790555 |
0.67 |
Coiled-Coil Domain Containing 146 |
||
|
cg20651681 |
VANGL2 |
ILMN_1715647 |
0.67 |
Vang-Like2 (Vangogh, Drosophila) |
||
|
cg06790324 |
SCG2 |
ILMN_1703178 |
0.66 |
Secretogranin II |
||
|
cg20651681 |
STGC3 |
ILMN_1807244 |
0.66 |
hypothetical STGC3 |
||
|
cg06790324 |
ABHD14B |
ILMN_2227533 |
0.66 |
Ab Hydrolase Domain Containing 14B |
||
|
cg20651681 |
TLL1 |
ILMN_1699814 |
0.66 |
Tolloid-Like 1 |
||
|
cg20651681 |
SOD1 |
ILMN_1662438 |
-0.65 |
Superoxide Dismutase 1, Soluble |
||
|
cg06790324 |
INPP5E |
ILMN_1811301 |
0.65 |
Inositol polyphosphate-5-phosphatase, 72 kDa |
||
|
|
||||||
|
Genes in bold have suggested role in fetal or placental growth and development 1 Pearson correlation coefficient (P ≤ 0.01) |
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|
Turan et al. BMC Medical Genomics 2012 5:10 doi:10.1186/1755-8794-5-10 |
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