Additional file 2.
EMT signature was derived by comparing gene expression of cell lines sorted into epithelial or mesenchymal like groups based on CDH1 and VIM expression (see Additional Figure 1). The top 200 up and down probes found most significant by ANOVA (P < 0.001) were selected to represent the EMT signature. The EMT signature contains known EMT drivers such as ZEB1 and ZEB2, TCF4, AXL. It also contains markers such as CDH1, CDH3 for epithelial phenotype and VIM, CDH2 and CDH4 for the mesenchymal phenotype.
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Loboda et al. BMC Medical Genomics 2011 4:9 doi:10.1186/1755-8794-4-9