Additional File 4.

Figure S3: Heatmap of 14 loci that are differentially methylated in proximal CRC compared to distal CRC. Unsupervised hierarchical clustering of the 14 loci (rows) in 24 CRC samples (columns). Thirteen of these loci were hypermethylated in proximal CRC compared to distal CRC. The two major clusters generated (top dendogram) in this analysis separated most of the proximal CRC tissues from the distal CRC tissues. Age at diagnosis (>45 yrs or = <45 yrs and the differentiation of the tumor (moderately differentiated or poorly differentiated) are shown above the heatmap.

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Kibriya et al. BMC Medical Genomics 2011 4:50   doi:10.1186/1755-8794-4-50