Table 5

15 miRNAs and target genes involved in the cancer-related functions

Cancer. related Function

PLS predicted Target genes in the respective functions

The nos. of cancer related miRNAs associated with the mRNA targets


Cancer

ANXA2, BHLHE40, CANX, CAPG, COTL1, CYBA, DDIT4, FTL, GPX1, GSTP1, IFITM1, MIF, MMP11, OAZ1, ODC1, S100A11, SLC12A8, SLC7A11, SOX4 and UBE2I (20)

15


Tumorigenesis

ANXA2, BHLHE40, CANX, CAPG, COTL1, CYBA, DDIT4, FTL, GPX1, GSTP1, IFITM1, MIF, MMP11, NUDT1, OAZ1, ODC1, PRDX2, S100A11, SLC12A8, SLC7A11, SOX4 and UBE2I (22)

15


Carcinoma

ANXA2, BHLHE40, CANX, COTL1, CYBA, FTL, GSTP1, IFITM1, MMP11, OAZ1, ODC1, S100A11 and SLC7A11 (13)

12


Malignant tumor

ANXA2, BHLHE40, CANX, COTL1, CYBA, FTL, GPX1, GSTP1, IFITM1, MIF, MMP11, OAZ1, ODC1, S100A11, SLC7A11 and SOX4 (16)

12


Primary tumor

ANXA2, BHLHE40, CANX, COTL1, CYBA, FTL, GPX1, GSTP1, IFITM1, MIF, MMP11, OAZ1, ODC1, PRDX2, S100A11, SLC7A11 and SOX4 (17)

12


Angiogenesis

ANXA2, CANX and GPX1 (3)

8


Li et al. BMC Medical Genomics 2011 4:44   doi:10.1186/1755-8794-4-44

Open Data