Open Access Highly Accessed Research article

Modeling microRNA-mRNA Interactions Using PLS Regression in Human Colon Cancer

Xiaohong Li12, Ryan Gill3, Nigel GF Cooper2, Jae Keun Yoo4 and Susmita Datta1*

Author Affiliations

1 Department of Bioinformatics and Biostatistics, University of Louisville, (485 E. Gray St.), Louisville, KY 40202, USA

2 Department of Anatomical Sciences and Neurobiology, University of Louisville, (500 S. Preston St.), Louisville, KY 40202, USA

3 Department of Mathematics, University of Louisville, (328 Natural Sciences Building), Louisville, KY 40292, USA

4 Department of Statistics, Ewha Womans University, (52 Ewhayeodae-gil, Seodaemun-gu), Seoul, 120-750, Republic of Korea

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BMC Medical Genomics 2011, 4:44  doi:10.1186/1755-8794-4-44

Published: 19 May 2011

Additional files

Additional file 1:

Differentially expressed miRNAs in human colon tissues. Supplemental Table 2 (S2): This file is a tab-delimited text file and contains 2 up-regulated and 31 down-regulated miRNAs with FDR corrected p-value less than 0.1 and absolute fold changes greater than 1.2. It also provides detailed information about each miRNA such as its name, expression values and description.

Format: TXT Size: 7KB Download file

Open Data

Additional file 2:

Differentially expressed mRNAs in human colon tissues. Supplemental Table 1 (S1): This file is a tab-delimited text file and contains 73 up-regulated and 63 down-regulated mRNAs with FDR corrected p-value less than 0.1 and absolute fold changes greater than 1.2 It also provides detailed information about each mRNA such as its name, expression values and description.

Format: TXT Size: 32KB Download file

Open Data