Table 2

Mean relative expression of genes1 on 22q11.2

Gene Name

Map

22q11.2 del

TOF

Control

RefSeq


COMT

22q11.21-q11.23

0.36 (0.04)

1.02 (0.15)

0.96 (0.09)

NM_000754; NM_007310

DGCR2

22q11.21

0.27 (0.10)

0.71 (0.23)

0.90 (0.25)

NM_005137

CRYBA4

22q11.2-q13.1

0.54 (006).

0.86 (0.32)

1.01 (0.10)

NM_001886

ZNF74

22q11.2

0.52 (0.01)

0.99 (0.12)

1.00 (0.15)

NM_003426

FLJ36561

22q11.23

0.40 (0.24)

1.18 (0.44)

1.00 (0.21)

NM_182520

CABIN1

22q11.23

0.52 (0.06)

0.53 (0.17)

0.99 (0.23)

NM_012295

ARVCF

22q11.21

0.57 (0.07)

1.01 (0.44)

0.92 (0.24)

NM_001670

FLJ14360

22q11.21

0.65 (0.08)

0.58 (0.17)

1.01 (0.13)

NM_032775

RUTBC2

22q11.23

0.69 (0.04)

0.92 (0.42)

0.94 (0.16)

GGTLA1

22q11.23

0.58 (0.13)

0.61 (0.22)

0.98 (0.28)

NM_004121

DGCR8

22q11.2

0.54 (0.11)

0.59 (0.25)

0.99 (0.11)

NM_022720

GGT1

22q11.23

0.70 (0.36)

1.19 (0.32)

0.94 (0.26)

NM_005265; NM_013421; NM_013430

MMP11

22q11.2

0.37 (0.18)

0.77 (0.33)

1.00 (0.17)

NM_001145938

TBX1

22q11.21

Not detectable

Not detectable

Not detectable

NM_005992


1. Expression levels from microarray (fold change) relative to the normalized control values set at 1, mean (+/- sd).

Bittel et al. BMC Medical Genomics 2011 4:1   doi:10.1186/1755-8794-4-1

Open Data