Table 1

Demographic and phenotypic characteristics of the study population.

Variable

Obese

Lean

p-value


N

17

17

-

Female (%)

9(53%)

12(70%)

-

Age (yrs)

52.2(10.2)

47(9.3)

0.1270

BMI at baseline (kg/m2)

44.8(8.1)

20.7(1.9)

0.0000

BP, diastolic (mm Hg)

84.4(8.2)

69.8(8.7)

0.0001

BP, systolic (mm Hg)

143.0(11.8)

119.1(12.3)

0.0000

Waist circumference (cm)

125.7(15.1)

77.7(7.3)

0.0000

Weight (kg)

127.6(26.5)

58.8(8.3)

0.0000

Body fat (%)

45.9(7.3)

22.0(6.9)

0.0000

Fat free mass (kg)

67.4(10.3)

45.7(7.9)

0.0000

Fat mass (kg)

59.5(19.9)

12.9(4.2)

0.0000

Fasting glucose (mmol/L)

6.3(2.2)

4.8(0.4)

0.0102

Insulin (pmol/L)

99.8(56.7)

27.6(11.0)

0.0001

HbA1c (%)

5.9(0.8)

5(0.4)

0.0002

HDL-cholesterol (mmol/L)

1.0(0.2)

1.6(0.3)

0.0000

LDL-cholesterol (mmol/L)

3.2(0.6)

3.3(0.9)

0.6441

Cholesterol (mmol/L)

5.1(0.8)

5.4(0.9)

0.2673

Triglycerides (mmol/L)

1.9(1.8)

0.9(0.5)

0.0399

Thyroid stimulating hormone (mU/L)

2.6(1.3)

1.9(1.6)

0.2073


Values for continuous measures are shown as average (standard error); p-values are obtained from two-sided Student's t-test, assuming unequal variances between groups.

Ghosh et al. BMC Medical Genomics 2010 3:56   doi:10.1186/1755-8794-3-56

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