Power analysis of the screening panel. For the power analysis of the screening panel, admixed-individual genotypes for a case only analysis using ANCESTRYMAP were simulated. A set of disease-predisposition loci were chosen using a resolution of four markers per Cm. A range of ethnicity relative risk (ERR) ratios, between 0.4 and .0.8, were set as the disease model parameters. Power was measured as the proportion of ANCESTRYMAP runs which identified the putative disease loci with genome log-factor >2. The power of the screening panel was compared to the 2000 AIMs panel which appeared in Tian et.al .
Shlush et al. BMC Medical Genomics 2010 3:47 doi:10.1186/1755-8794-3-47