Three dimensional PCA plot of the unifrac distance in relation to diabetes. Principle component analysis based upon a unifrac analysis of the sequencing data was utilized. Based upon this PCA analysis the primary 3 vectors are plotted in 3 dimensions. The percent variability explained by each vector is indicated in parenthesis in the figure. Based upon the primary vector a t-test was utilized to determine if there was significant variation between diabetic samples. The separation across the primary vector was found to be significant (p = 0.003) indicating that the community structure of ulcers in subjects with diabetics may be different from those of non-diabetics.
Smith et al. BMC Medical Genomics 2010 3:41 doi:10.1186/1755-8794-3-41