Table 3

Modules correlated with metabolic traits in subcutaneous (SAT) and visceral adipose tissue (VAT)

Tissue

Module ID

Correlated trait

No. of genes in module

Correlation

coefficient

P-value


SAT

31

Gender

14

6.6 × 10-66

4

HDL cholesterol

308

-0.58

2.5 × 10-7

13

Glucose

28

-0.51

7.0 × 10-6

Triglycerides

-0.50

1.8 × 10-5

8

HDL cholesterol

87

-0.49

2.7 × 10-5

39

HDL cholesterol

7

-0.49

3.0 × 10-5

VAT

31

Gender

14

8.2 × 10-60

40

Insulin

12

-0.54

4.3 × 10-6

BMI

-0.49

2.8 × 10-5

9

Glucose

103

0.50

2.1 × 10-5


Only those modules significantly correlated to a metabolic trait after Bonferroni correction are shown, with the names of the modules, the traits to which they were correlated, the number of genes that comprise the module, and the Spearman rank correlation coefficient between the value of the module - i.e. the average of all the probes in the module - and the trait. To calculate p-values for association between a module and gender we used a students T-test.

Wolfs et al. BMC Medical Genomics 2010 3:34   doi:10.1186/1755-8794-3-34

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