Table 1

Clinical and plasma parameters of the study population

All individuals

Individuals without type 2 diabetes and NASH

Type 2 diabetes patients

NASH patients

Individuals with type 2 diabetes and NASH

No. of individuals/Mean (SD)

Minimal/maximal values

No. of individuals/Mean (SD)

Minimal/maximal values

No. of individuals/Mean (SD)

Minimal/maximal values

No. of individuals/Mean (SD)

Minimal/maximal values

No. of individuals/Mean (SD)

Minimal/maximal values


Number of individuals

75

29

25

41

20

Male/female

22/53

7/22

7/18

12/29

4/16

Age (years)

44.4 (9.9)

17 - 67

40.3 (9.2)

17 - 54

48.2 (9.4)

28 - 67

45.8 (8.9)

28 - 65

46.5 (8.1)

28 - 65

BMI (kg/m2)

46.5 (9.6)

34.6 - 73.6

42.6 (6.5)

34.6 - 56.8

49.4 (11.4)

34.8 - 73.6

48.7 (10.8)

34.8 - 73.6

49.6 (12.1)

34.8 - 73.6

Glucose (mmol/l)

6.60 (2.1)

4.3 - 14.5

5.53 (0.49)

4.3 - 6.5

8.73 (2.5)

4.3 - 14.5

7.16 (2.56)

4.3 - 14.5

8.8 (2.72)

4.3 - 14.5

Insulin (mU/l)

19.3 (10.9)

3.8 - 53

16.7 (8.8)

5.6 - 37

20.6 (13.1)

5.5 - 53

20.9 (11.1)

3.8 - 49

20.4 (10.9)

3.8 - 49

HbA1c

6.58 (1.39)

5.1 - 12.1

6 (0.54)

5.1 - 7.2

7.9 (1.78)

5.3 - 12.1

6.88 (1.65)

5.2 - 12.1

7.85 (1.88)

5.2 - 12.1

Total cholesterol (mmol/l)

5.08 (1.1)

3 - 9.8

4.93 (0.65)

3.5 - 6.1

5.15 (1.43)

3.5 - 9.8

5.08 (1.23)

3 - 9.8

5.2 (1.5)

3 - 9.8

HDL cholesterol (mmol/l)

0.98 (0.38)

0.5 - 2.8

1.05 (0.3)

0.6 - 1.9

0.8 (0.23)

0.5 - 1.3

0.93 (0.44)

0.5 - 2.8

0.78 (0.22)

0.5 - 2.8

LDL cholesterol (mmol/l)

3.22 (1.02)

1.1 - 7.4

3.16 (0.86)

1.1 - 4.3

3.29 (1.18)

1.5 - 7.4

3.17 (1.06)

1.5 - 7.4

3.32 (1.25)

1.5 - 7.4

TG (mmol/l)

2.26 (2.12)

0.63 - 16.4

1.67 (0.95)

0.63 - 4.2

3.31 (3.46)

0.88 - 16.4

2.73 (2.71)

0.88 - 16.4

3.56 (3.67)

0.88 - 16.4

NEFA (mmol/l)

0.64 (0.32)

0.12 - 1.66

0.52 (0.34)

0.12 - 1.66

0.72 (0.3)

0.16 - 1.33

0.71 (0.28)

0.21 - 1.33

0.76 (0.29)

0.21 - 1.33

ALAT (U/l)

25.7 (16.5)

6 - 124

19.8 (6.3)

7 - 37

32.3 (23.1)

10 - 124

27.7 (19.3)

6 - 124

32.4 (24.8)

6 - 124

ASAT (U/l)

25.3 (12.9)

7 - 72

21.1 (11.6)

7 - 50

28.9 (15.4)

8 - 72

28.4 (13)

8 - 72

30.7 (16)

8 - 72

CRP (mg/l)

10.2 (8.5)

1 - 37

9.9 (9.2)

1 - 37

13.1 (10)

1.7 - 35

10 (8.2)

1.7 - 35

12.8 (10.2)

1.7 - 35


Data are means ± standard deviation (SD) and the minimal and maximal values for each trait. Data are given for all individuals, individuals without type 2 diabetes or NASH, type 2 diabetes patients, NASH patients, and individuals with both type 2 diabetes and NASH. Patients with type 2 diabetes are 36, 37, 40, 42, 43, 49, 51, 54, 55, 57, 60, 63, 64, 65, 69, 75, 77, 78, 79, 85, 87, 97, 101, 103, and 110 - IDs are concordant with the IDs used submitted to the Gene Expression Omnibus database. Patients with NASH are 38, 42, 43, 44, 45, 47, 49, 51, 52, 53, 54, 57, 58, 60, 62, 63, 64, 65, 69, 72, 75, 78, 79, 83, 85, 87, 88, 92, 93, 95, 97, 99, 100, 101, 102, 103, 104, 105, 107, 110, and 113. TG, triglycerides; NEFA, non-esterified fatty acid; ALAT, alanine aminotransaminase; ASAT, aspartate aminotransaminase; CRP, C-reactive protein; NASH, non-alcoholic steatohepatitis.

Wolfs et al. BMC Medical Genomics 2010 3:34   doi:10.1186/1755-8794-3-34

Open Data