Table 2

Methylation Associations

Ilmn CpG ID

Gene

Gene Function

Location

coef

exp(coef)

se(coef)

z

Pr(> |z|)

Q value


cg01172656

NRBF2

Transcription regulation

10:64563126

0.631

1.880

0.136

4.653

3.266 × 10-06

0.031


cg18346038

PIGU

GPI-anchor biosynthesis

20:32728489

0.624

1.867

0.136

4.603

4.164 × 10-06

0.031


cg00117172

RUNX3

Transcription regulation

1:25128425

0.682

1.977

0.150

4.548

5.427 × 10-06

0.031


cg02068676

COBRA1

Negative regulation of transcription

9:139269304

0.662

1.938

0.149

4.447

8.703 × 10-06

0.037


cg00025138

MAP3K9

Mixed-lineage kinase

14:70345670

0.543

1.721

0.125

4.335

1.457 × 10-05

0.046


cg03221776

MFSD3

Transmembrane transport

8:145704779

0.520

1.682

0.121

4.308

1.644 × 10-05

0.046


cg12181621

HIST1H3I

Nucleosome assembly

6:27948047

0.558

1.748

0.132

4.216

2.486 × 10-05

0.048


cg03752885

DAPK3

Induction of apoptosis

19:3920736

0.492

1.636

0.118

4.189

2.798 × 10-05

0.048


cg12688215

KTI12

ATP binding

1:52271816

0.446

1.563

0.107

4.175

2.976 × 10-05

0.048


cg07341907

UNC13B

Exocytosis

9:35151971

0.606

1.833

0.145

4.169

3.056 × 10-05

0.048


cg26850145

ZBTB5

Transcription regulation

9:37455023

-0.485

0.616

0.117

-4.142

3.441 × 10-05

0.048


cg21312090

TRPS1

NLS-bearing substrate import into nucleus

8:116750901

0.441

1.555

0.107

4.135

3.543 × 10-05

0.048


cg23266266

DCUN1D4

-

4:52403466

0.560

1.751

0.136

4.117

3.847 × 10-05

0.048


cg04466870

SFXN4

Transmembrane transport

10:120915170

0.477

1.611

0.116

4.102

4.092 × 10-05

0.048


cg16898420

PPAPR3

Catalytic activity

9:102830899

-0.711

0.491

0.175

-4.066

4.786 × 10-05

0.048


cg17260725

CCNB2

Cell division

15:57184580

0.523

1.687

0.129

4.0596

4.915 × 10-05

0.048


cg17428423

DOC2A

Regulation of calcium ion-dependent exocytosis

16:29929633

-0.728

0.483

0.180

-4.053

5.049 × 10-05

0.048


cg18731014

ZNF639

Transcription regulation

3:180524284

0.556

1.744

0.137

4.050

5.122 × 10-05

0.048


cg21830413

VPS26

Protein transport

10:70554257

0.472

1.604

0.117

4.036

5.430 × 10-05

0.048


Cox-Regression analysis results of CpGs, with FDR (q value) < 0.05, for time to develop nephropathy. (Location given as Chromosome:Base Pair (Build Hs 36.1))

Bell et al. BMC Medical Genomics 2010 3:33   doi:10.1186/1755-8794-3-33

Open Data